Assistant Professor
https://www.linkedin.com/in/aruna-sivaram-714006a3/
Dr. Aruna Sivaram has completed her Ph.D. from National Institute of Virology, Pune. Her research interests include drug discovery, molecular pathology of diseases like cancer, and control of arbovial vectors.
Qualifications
- Ph.D. in Biotechnology | National Institute of Virology, Pune | 2006 – 2011
- M.Sc. in Biotechnology | University of Madras, Chennai, Tamil Nadu | 2004 - 2006
- B.Sc. in Industrial Microbiology, Biochemistry | University of Kerala, Thiruvananthapuram, Kerala | 2001 - 2004
Experience
| Teaching | 2.5 years |
| Industry research | 7.5 years |
| Research | 4 years |
Career Highlights
Work Experience (Senior Research Scientist, Lupin Ltd, Pune)
- Responsible for entire in vitro pharmacology of drug discovery process for several projects
- Identification of new targets for certain therapeutic indications like cancer and metabolic diseases
- Worked in a number of projects ranging from infectious diseases, metabolic disorders, asthma and cancer
- Responsible for overseeing screening of different new chemical entities in cell based and cell-free systems
- Responsible for assay developments in cell based as well as cell-free systems and trouble-shoot as and when needed
- Shortlisting of compounds for further discovery/development processes
- Worked on doctoral thesis titled ‘Studies on the Densoviruses of Aedes mosquitoes and their interaction with susceptibility of mosquitoes to Chikungunya virus’
- Expertise in working in BSL3+ facility for highly infectious pathogens
- Development of molecular diagnostics for the identification of viral pathogens
- Worked on project titled ‘Investigation of bat populations from India for the detection of highly pathogenic viruses and paramyxoviruses’, funded by CDC, Atlanta
Publications
- Sivaram A, Barde PV, Kumar SR, Yadav P, Gokhale MD, Basu A, Mourya DT. Isolation and characterization of densonucleosis virus from Aedesaegypti mosquitoes and its distribution in India. Intervirology. 2009. 52 (1); 1-7.
- Sivaram A, Barde PV, Gokhale MD, Singh DK, Mourya DT. Evidence of co-infection of chikungunya and densonucleosis viruses in C6/36 cell lines and laboratory infected Aedesaegypti (L.) mosquitoes. BMC, Parasites and Vectors. 2010. Oct 12; 3(1):95.
- Gurav YK, Raut CG, Yadav PD, Tandale BV, Sivaram A, Pore M, Basu A Mourya DT, Mishra AC. Buffalo pox in human and animals in Western Maharashtra, India. Prev Vet Med. 2011 Jul 1; 100(3-4):242-7. 2011 Apr 20.
- Raut C, G, Yadav P, D, Towner J, S, Amman B, R, Erickson B, R, Cannon D, L, Sivaram A, Basu A, Nichol S, T, Mishra A, C, Mourya D, T: Isolation of a Novel Adenovirus from Rousettusleschenaultii Bats from India. Intervirology 2012;55:488-490. doi: 10.1159/000337026
- VidyaRamdas, RashmiTalwar, Moloy Banerjee, AdvaitArun Joshi, Amit Kumar Das, Deepak SahebraoWalke, PrashantBorhade, UshaDhayagude, Rajesh Loriya, Ganesh Gote, ApparaoBommakanti, ArunaSivaram, Gautam Agarwal, ArnabGoswami et al., Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate. J. Med. Chem. 2019, 62, 10563−10582.
FDP
- FDP on Proteomics conducted by NPTEL in 2020
- Online Faculty Development Program on “Education 4.0: Teachers Training (Version 1.0) for TCSiON LMS” conducted by MIT-ADT University.
- Faculty Development Program on "Online Teaching - Learning Pedagogy" conducted by MIT-ADT University.