Ph.D.

  • Sunita Fernandes

    Research Area: Plant Biotechnology

    Research Topic: Nanotechnology based bio fertilizer and pesticide for agrochemical Industry.

    Research Interest

  • Deepali Ghorpade

    Research Area: Genomic Data Analysis

    Research Topic: Computational analysis of Next generation sequencing data using big data analytics approach.

    Publications:

    1. “Obstacle Detection and Avoidance Algorithm for Autonomous Mobile Robot using 2D LiDAR”, IEEE International Conference on Computing, Communication, Control and Automation (ICCUBEA), ISBN: 978-1-5386-4008-1, 2017.

    2. “Human Skin Color Detection Algorithm Optimization with CUDA”, IEEE International Conference on Computing, Communication, Control and Automation (ICCUBEA), ISBN: 978-1-5386-4008-1, 2017.

    3. Big data analytics for handling NGS data and its applications in identifying cancer mutations (Advances in Bioengineering, Springer book chapter).

    4. “The Obstacle Detection and Avoidance Algorithm for Robotic System using 2DLiDAR and Embedded Linux”, International Journal of Control Theory and Applications, pp.693-699, 2017.

    Presentations (Oral):

    1. Obstacle Detection and Avoidance Algorithm for Autonomous Mobile Robot using 2D LiDAR (ICCUBEA -2017).

    2. Human Skin Color Detection Algorithm Optimization with CUDA (ICCUBEA -2017).

    Research Interest

  • Mr. Amol Kahandal

    Research Area: Biomaterials

    Research Topic: Synthesis of metal oxide nanoparticles using bio-templates and study of their biological applications

    Publications: A sensitive image-based optical detection of heavy metal ions using green synthesized silver nanoparticles has been published in the International Journal of Environmental Science and Technology (Springer)

    Research Interest

  • Sagarika Saha

    Research Area: Next Generation Sequencing and Molecular Oncology

    Research Topic: Novel biomarker and therapeutic agents’ discovery against cancer

    Awards:

    “1st Position award for the best innovative and novel research idea” in Poster Presentation on ‘Study of the neuroprotective potential associated with dietary supplementation of Coenzyme Q10 using Drosophila melanogaster model of Alzheimer’s disease’ in ARIC- Annual Research and Innovation Conclave, Institute of Advanced Research, Gandhinagar.

    Presentations:

    1. ‘Coenzyme Q10 possess neuroprotective potential in Drosophila melanogaster model of Alzheimer’s disease’ at ‘The Indian Drosophila Research Conference (InDRC)’, Indian Institute of Science Education and Research Kolkata (IISER K), Kolkata, West Bengal, India.

    Research Interest

  • Vandana Yadav

    Research Area: Cancer Biology

    Research Topic: Role of unfolded protein response in gynaecological cancers

    Awards: CSIR NET JRF , ARS NET

    Research Interest

  • Ms. Sneha Bhosale

    Research Area: Agricultural biotechnology

    Research Topic: Genetic diversity analysis of Xanthomonas campestris pv. viticola causing
    bacterial leaf spot in grapes and its management.

    Research Interest

  • Madhavi P. Bhongale

    Research Area: Biomedical Imaging

    Research Topic: Design and development of multi-disease detection model using Diagnostic Imaging Technology

    Publications:

    1. Madhavi P. Bhongale, Renu Vyas, Role of BioJava in the department of Bioinformatics Tools Advances in Bioengineering, Springer Nature (2020)

    2. Off-line Signature Verification Using Artificial Neural Network International Journal of Emerging Technology and Advanced Engineering, Volume 3, Issue 9, September 2013 ISSN: 2250-2459, ISO 9001:2008 © IJETAE International Journals: www.ijetae.com, Madhavi D. Malekar, Sachin Patel.

    3. Off-line Signature Verification Using Artificial Neural Network& Error Detection International Journal of Computer Science and Information Technologies, Volume5, Issue 4, 2014, ISSN : 0975-9646 © IJCSIT International Journals: www.ijcsit.com, Madhavi D. Malekar, Sachin Sohara.

    4. Off-line Signature Verification Using ANN in Futurizm 17 organized by PDEA’s College of Engineering, Pune.

    Presentations(Oral/Poster):

    1. Presented paper on Detection of infectious diseases from chest X-ray and CT Images using a new Optimized Classifier in International Conference on Recent Trends in Bioengineering (ICRTB 2018) organized by MIT School of Bioengineering Sciences & Research, Pune on 12-13 February 2022.

    Research Interest

  • Manoj K. Sabnani

    Research Area: Onco Immunology, Antibody Engineering, Drug Discovery.

    Research Topic: Antibody discovery/engineering using in silico tools.

    Publications:

    1. Manoj K. Sabnani, Robin Rajan, Bradley Rowland, Vikram Mavinkurve, Laurence Wood, Alberto A. Gabizon, Ninh M. La-Beck.
    Liposome promotion of tumor growth and angiogenesis is associated with modulation of antitumor immune response. Nanomedicine: Nanotechnology, Biology and Medicine, Volume 11, Issue 2, 259 – 262. DOI: http://dx.doi.org/10.1016/j.nano.2014.08.010.

    2. Robin Rajan, Magdalena Karbowniczek, Haley Pugsley, Manoj K. Sabnani, Aristotelis Astrinidis, Ninh M. La-Beck.
    Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry. Imagestream methods: Cytometry Part A, Volume 87, Issue 5, 451 - 458. DOI: 10.1002/cyto.a.22652

    3. Devin B. Lowe, Camille K. Bivens, Alexis S. Mobley, Christian E. Herrera, Amanda L. McCormick, Timea Wichner, Manoj K. Sabnani, Laurence M. Wood & Jon A. Weidanz
    TCR-like antibody drug conjugates mediate killing of tumor cells with low peptide/HLA targets, mAbs, 9:4, 603-614, DOI: 10.1080/19420862.2017.1302630

    4. Anuraj N, Sabnani Manoj K, Mukesh Yadav, Jyotsana Kharate J, Deepika Sharma R and Rachna Chourasia J. (2012).
    Identification and characterization of proteases and amylases producing Bacillus licheniformis strain EMBS026 by 16S rRNA Gene Sequencing. International journal of Microbiology Research ISSN: 0975-5276 & E-ISSN: 0975-9174, Volume 4, Issue 5, 2012, 227-231.

    5. Robin Rajan, Manoj K. Sabnani, Laurence M. Wood, Vikram   Mavinkurve, Alberto A. Gabizon and Ninh M. La-Beck.
    Pegylated liposomal alendronate: The impact of the drug cargo on carrier-induced       immune modulation. American Association of Cancer Research. DOI: 10.1158/1538-7445.AM2016-4008 Published July 2016

    6. SSS Peri, Manoj K Sabnani, MU Raza, S Ghaffari, S Gimlin, DD Wawro. Detection of specific antibody-ligand interactions with a self-induced back-action actuated nanopore electrophoresis sensor Nanotechnology 31 (8), 085502

    7. J Kaur, MK Sabnani, BY Stephens, D Nandadeva, JA Weidanz, PJ Fadel Peripheral Blood Mononuclear Cell‐Derived Superoxide Production, Spontaneous Baroreflex Sensitivity, and Vascular Function in Chronic Kidney Disease Patients. The FASEB Journal 34 (S1), 1-1.

    8. Book Chapter: Reference Module in Biomedical Sciences. Stem cells as Drug delivery vehicle DOI:10.1016/B978-0-12-801238-3.65443-0

    9. Serkan Yaman, Harish Ramachandramoorthy, Gizem Oter, Daria Zhukova, Tam Nguyen, Manoj Kumar Sabnani, Jon A Weidanz* and Kytai Truong Nguyen* Melanoma Peptide MHC Specific TCR Expressing T-Cell Membrane Camouflaged PLGA Nanoparticles for Treatment of Melanoma Skin Cancer. Frontiers in Bioengineering & Biotechnology Section. (September 2020)

    10. Sai Santosh Sasank Peri, Manoj Kumar Sabnani, Muhammad Usman Raza, Elizabeth L. Urquhart, Soroush Ghaffari, Jung Soo Lee, Min Jun Kim, Jon Weidanz, George Alexandrakis. Quantification of Low Affinity Binding Interactions between Natural Killer Cell Inhibitory Receptors and Targeting Ligands with a SelfInduced Back-Action Actuated Nanopore Electrophoresis (SANE) Sensor.. IOP Nanotechnology.

    11.  Zaki, Magdi E.A., Sami A. Al-Hussain, Vijay H. Masand, Manoj K. Sabnani, and Abdul Samad. 2021. "Mechanistic and Predictive QSAR Analysis of Diverse Molecules to Capture Salient and Hidden Pharmacophores for Anti-Thrombotic Activity" International Journal of Molecular Sciences 22, no. 15: 8352. https://doi.org/10.3390/ijms22158352

    Research Interest

  • Mrs. Pradnya Gurav

    Research Area: Stem Cell Biology

    Research topic: Role of (n-3 PUFAs) in reducing side effects of chemotherapy

    Publications:

    Kumar J, Gurav R, Kale V, Limaye L (2014) Exogenous Addition of Arachidonic Acid to the Culture Media Enhances the Functionality of Dendritic Cells for their Possible Use in Cancer Immunotherapy. PLoS ONE 9(11): e111759. doi:10.1371/journal.pone.0111759

    Presentations (Oral/poster):

    Poster presented on Preparation of biocompatible and bactericidal films using silver doped galactomannan/gelatin/PVA nanocomposite for biomedical applications in 3 rd International Conference on Recent Trends in Bioengineering (ICRTB 2020) organized by MIT School of Bioengineering Sciences & Research, Pune on 31 st January 2020.

    Research Interest

  • Mr. Surojit Sadhu

    Research Area: Chemoinformatics and Drug Discovery

    Research topic: Using Chemoinformatics and Machine learning to discover novel anti-viral molecules.

    Presentations (Oral/poster):

    1. As founder of Advent Informatics I have delivered numerous training session on chemoinformatics tools.

    2. Delivered lecture on chemoinformatics and drug discovery in the Drug Discovery Hackathon training organized the Ministry of Human Resource and Development in association with CSIR and AICET.

    3. Delivered a talk on “Evidence-based toxicity alerts assisting drug discovery in real-time” in OpenTox Asia-2019 organized at CSIR- Indian Institute of Chemical Technology

    4. Delivered a talk on “Recent Advances in Chemoinformatics and Drug Discovery” in Drug Discovery India 2019 organized by Select Biosciences.

    5. Presented poster titled “Using Information models for data analysis and Workflow” in SSX India – 2017

    6. Presented a poster on “ViMAL- Virus Molecular Association from Literature” in Drug Info meet 2009

    Research Interest

  • Mrs. Nandini Sandeep Kotharkar

    Research Area: Phytochemistry and Computational Phytochemistry

    Research Topic: Computational analysis of phytochemicals extracted from the flowers ofNycthanthesarbortristis L. for the design and development of leadcompounds for rheumatoid arthritis.

    Presentation(Oral/poster):

    1. Presented paper on“Phytochemical and Pharmacological evaluation of Nyctanthes arbortristis L,” in International Conference on Recent Trends in Bioengineering (ICRTB 2019) organized by MIT School of Bioengineering Sciences & Research, Pune on 16 February 2019.

    2. Presented a poster on “Phytochemical analysis of methanolic bark extract of Nyctanthes arbor-tristis L for evaluation of potential bioactive compounds”, in International Conference on Recent Trends in Bioengineering (ICRTB 2020) organized by MIT School of Bioengineering Sciences & Research, Pune on 31st January 2020.

    3. Presented a poster on“Phytochemical extraction of fruit peels and its comparative analysis”, in International Conference on Recent Trends in Bioengineering (ICRTB 2020) organized by MIT School of Bioengineering Sciences & Research, Pune on 31st January 2020.

    Research Interest

  • Ms. Vedashree Sirdeshmukh

    Research Area: Biosensor, Microbiology, Nanotechnology

    Research topic: Design and Development of biosensor for detection of bacterial pathogens

    Publications:

    1. VedashreeSirdeshmukh, ChandrakantTagad, Renu Vyas, Anup Kale, Nanomaterial-Enabled Rapid Electrochemical Biosensors for Bacterial Pathogens, (2020) Springer Nature, “Advances in Bioengineering” ISBN 978-981-15-2063-1, 171-182.

    Presentations (Oral/poster):

    1. VedashreeSirdeshmukh. ChandrakantTagad, Renu Vyas, Anup Kale,”Nanomaterial-Enabled Rapid Electrochemical Biosensors for Bacterial Pathogens”,16 Feb 2019,MIT School of Bioengineering Sciences and Research.

    2. VedashreeSirdeshmukh, ChandrakantTagad,”Electrochemical detection of E. coli using polysaccharide modified ZnO nanoparticles”,31 Jan -1 Feb 2020,MIT School of Bioengineering Sciences and Research.

    3. VedashreeSirdeshmukh, ChandrakantTagad,” Electrochemical detection of E. coli using polysaccharide modified ZnO/Ag nanoparticles”,4-6 March 2020,Tripura University.

    Research Interest

  • Mrs. Yogita Ranade

    Research Area: Next generation sequencing,Cancer genomics

    Research Area: Agriculture Microbiology

    Research topic: Bioremediation of pesticide and microbial biological control agents from vineyard

    Awards:

    1. First prize for oral presentation in 2nd International conference for Recent Trends in Bioengineering held at MIT School of Bioengineering Sciences & Research, Pune, India on the topic, “Application of Trichodermaand Bacillus during initial berry developmental stages inhibits epiphytic colonization of grape berries by Cladosporium spp., a post-harvest pathogen”.

    2. First prize for oral presentation in 3rd International conference for Recent Trends in Bioengineering held at MIT School of Bioengineering Sciences & Research, Pune, India on the topic,“Preliminary studies on possible application of Kocuria sp. in plant growth promotion and bioremediation”.

    Presentations (Oral/Poster):

    1. Oral presentation-Yogita R, Indu S, Madhura C, Vijayshree C and Pranav P (2019). Application of Trichodermaand Bacillus during initial berry developmental stages inhibits epiphytic colonization of grape berries by Cladosporium spp., a post-harvest pathogen. 2ndInternational conference for Recent Trends in Bioengineering held at MIT School of Bioengineering Sciences & Research, Pune, India (16th January 2019)

    2. Oral presentation-Yogita R, Indu S, Madhura C, Sujoy S, Raviraj S and Pranav P (2020). Preliminary studies on possible application of Kocuria sp. in plant growth promotion and bioremediation. 3rd International conference for Recent Trends in Bioengineering held at MIT School of Bioengineering Sciences & Research, Pune, India (31st January and 1st February 2020)

    Research Interest

  • Mrs. Navya Sethu

    Research Area: Sensor development

    Research topic: Design and development of portable systems for environmental monitoring and microbial disinfection

    Patent:

    1. Provisional Indian Patent on Device and assay for detection of antibiotics in industrial effluents, dated 16/09/2019 with Application No. 201920137177

    Publications:

    1. N. Sethu, R. Vyas. (2020). Overview of Machine Learning Methods in ADHD Prediction. In R. Vyas (Ed.), Advances in Bioengineering (1 ed.): Springer Singapore. pp. 51-72

    Presentations(Oral/poster):

    1. Presented paper on Development Of A Genetic Programming Based Model For Prediction Of Attention Deficit Hyperactivity Disorder in International Conference on Recent Trends in Bioengineering (ICRTB 2019) organized by MIT School of Bioengineering Sciences & Research, Pune on 16 February 2019.

    2. Presented paper on Classification Model for predicting disease stage: ADHD Case Study in International Conference on Recent Trends in Bioengineering (ICRTB 2018) organized by MIT School of Bioengineering Sciences & Research, Pune on 17 February 2018.

    Research Interest

  • Ms. Nilofer Karim Shaikh

    Research Area: Big data (Cancer-omics)

    Research topic: Big data integrated environment for computational analysis of Cancer-omics data

    Awards:

    1.Participated and Won 1st Prize (Oral Presentation) in 2nd International Conference on Recent trends in Bioengineering (ICRTB 2019).

    2. Participated and won best e-poster invirtual International Conference on Basic and Translational Cancer Research: Novel Ideas and Approaches; ICBTCR2020.

    Publications:

    1. Under review A Review on Computational Analysis of Big Data in Breast Cancer for Predicting Potential Biomarkers

    Presentations (Oral/poster):

    1. Identification of Oncogene Biomarker by Profiling TCGA Omics Data Breast and Ovarian Cancer for Personalized Medicine organized by Cancer Education and Research (ACAR), school of life sciences, B.S. AbdurRahmenCresent institute of science and technology, Chennai India.

    2. Identification of oncogenic biomarker panels by profiling TCGA omics data for Breast cancer personalized medicine 3rd International Conference On Recent Trends In Bioengineering ( ICRTB 2020 )

    3. Identification of Oncogenic Biomarkers for Ovarian Cancer by Integrated Text Mining and Cancer Omics data organized by 2ndInternational Conference on Recent trends in Bioengineering (ICRTB 2019) organized by MIT School of Bioengineering Sciences and Research (MITBIO)

    Research Interest

  • Ms. Rucha Wadapurkar

    Research Area: Next generation sequencing,Cancer genomics

    Research topic: Computational analysis of next generation sequencing data and its applications in clinical oncology of ovarian cancer

    Awards:

    “ACER- Cancer innovative award for best innovative and novel idea” for oral presentation on Computational analysis of targeted sequencing data of ovarian cancer cell lines in International conference on basic and translational cancer research: novel ideas and approaches.

    Publications:

    1. Computational analysis of next generation sequencing data and its applications in clinical oncology (Informatics in medicine unlocked, Elsevier, volume 11).

    2. Big data analytics for handling NGS data and its applications in identifying cancer mutations (Advances in Bioengineering, Springer book chapter).

    3. Identification of ovarian cancer mutations by computational analysis of targeted sequencing data and their impact on protein structure and function (Under review).

    Presentations (Oral):

    1. Identification of ovarian cancer mutations using next generation sequencing (ICRTB-2018).

    2. Computational analysis of whole exome sequence data to identify ovarian cancer mutations (ICRTB-2019).

    3. Computational analysis of targeted sequencing data of ovarian cancer cell lines (ICBTCR-2020).

    Research Interest

Research scholars are currently working on interdisciplinary fields of engineering, biology and chemistry.

Ms. Rucha Wadapurkar, PhD research scholar

Conference Paper & Poster Presentation-

Presented poster entitled “Development of software tool for prediction of signal peptidesand promoter region motifs in defense responsive Subtilisin-like Protein of Glycine max (Soyabean)” at International conference held at Walchand College, Solapur.

Presented paper entitled “In silico Characterization and Docking of α- Conotoxin Mr1.7a from Conus marmoreus Targeting Neuronal nAChR α3β2” at National conference held at Shivaji University, Kolhapur.

Publication-

Publisher paper entitled “In silico drug design for Staphylococcus aureus and development of host-pathogen interaction network” in Elsevier journal.
Mr. Krishna Vadher

Host-pathogen interaction netwrok of S. aureus and Human

Pathogens have always intrigued us with their diverse mechanisms to overcome host defense mechanisms. Having associated with research work on pathogens right from lower classes, made pathogens as the prime focus for all my further studies. I worked with an emerging foodborne pathogen Listeria, during my post-graduation on the topic: Effect of Simultaneous stress on the protein expression of Pathogenic Listeria spp. To find answer to some more of My questions, I chose Listeria as my organism of interest to work with for my doctorate studies.Currently pursuing my Doctorate at the School of Bio-engineering on the topic “Deconstructing Listeria Pathogenesis by molecular approaches”. In silico Characterization and Docking of α- Conotoxin Mr1.7a from Conus marmoreus Targeting Neuronal nAChR α3β2
Ms. Neha Agrawal

She is currently working in the field of Biodiesel.

Publication- Presented Poster at UGC sponsored National Conference on Bioremediation- Recent trends & Future prospects organized by the Department of Microbiology in collaboration with Microbiologists Society- India, Mumbai University on 9th August 2014.

Ms. Nilofer Karim Shaikh
She is currently working in the field of “Computational Analysis Of Proteomic Data of Ovarian Cancer”.

Publication-

Computational analysis of BACE1 involved in Alzheimer’s disease using zebra fish (Daniorerio) as a model.

Docked complex of Cibacron Blue show a potential inhibitor againsed 3D structure of BACE-1

Project-

Homology Modeling and Procheck Analysis of Pfemp1 involved in Malaria

Secondary structure of Pfemp1 protein using SOPMA.

Designing And Development Of Novel Inhibitor For FALCIPAIN2 Involved In Malaria

Mrs. Navya Sethu
Currently working on the ‘Design and Development of a Biomedical Device to be used in Clinical Applications’.

Background- Electronics and Instrumentation.

Project- Controlling an industrial process using state estimation technique (Observer Design), using LabVIEW The observer plays an important role during monitoring of process, so that can provide better estimation performance, as well as fault detection in control devices that may cause structural changes of the process model.

Conference- Presented paper on ‘Observer Design for Coupled Tank Process’ in the Third International Conference on Intelligent Science & Technology (IIST 2011)organized by Sun College of Engineering & Technology, Nagercoil, TamilNadu.