Introduction
The accurate and on-time diagnosis of diseases is essential for its early treatment. Most of the currently used diagnostic techniques are laboratory bound, involve complex procedures, require sophisticated instruments, and expert personal to operate them. Thus, it is imperative to develop a sensitive, selective, affordable, robust, and portable biosensors for point-of-care diagnostics tools.Biosensors are electronic devices in which biomolecules such as enzymes, antibodies, nucleic acids, whole cells, etc. are used as a sensing element.
The development of a simple, reliable, and low-cost sensors for the analysis of environmental contaminants is also equally important owing to the severe health hazards caused by environmental pollutants. Our research group focuses on the development of reliable, low-cost sensing tools for the detection of food, water, and hospital-borne pathogens, detection of clinical biomarkers, and environmental pollutants such as antibiotics, pesticides, and heavy metal ions. We also work on the synthesis of functional nanomaterials tofabricate asensitive and selective biosensor for a wide range of applications.
Patents:
1. Invention Title: Device and assay for detection of antibiotics in industrial effluents; Applicants: Sreya K. Swaroop Mhasawade, Navya Sethu, Chandrakant Tagad, Renu Vyas. Application no. 201921037177
Publications:
1. Lokesh Sharma, Shubhankar Gouraj, Pranit Raut, Chandrakant Tagad, Development of a surface-modified paper-based colorimetric sensor using synthesized Ag NPs-alginate composite, Environmental Technology (2020) 1–10.
doi:https://doi.org/10.1080/09593330.2020.1732471
2. Tahsin Bennur, Chandrakant Tagad, R. C. Aiyer, Atul Kulkarni, Smita Zinjarde, A sensitive and selective optical detection of Ni2+ based on gold nanoparticles synthesized using Nocardiopsis, Optical Materials, 2019, 98, 109447.
doi:https://doi.org/10.1016/j.optmat.2019.109447
3. Chandrakant Tagad, Hyo Hyun Seo, Rucha Tongaonkar, Yeong Wook Yu, Jeong Hun Lee, Medini Dingre, Atul Kulkarni, Hassan Fouad, Shafeeque Ahmed Ansari, and Sang Hyun Moh. Green Synthesis of Silver Nanoparticles Using Panax Ginseng Root Extract for the Detection of Hg2+, Sensors and Materials, 2017, 29 (2), 205-215. http://dx.doi.org/10.18494/SAM.2017.1475
4. Vedashree Sirdeshmukh, Chandrakant Tagad, Renu Vyas, Anup Kale. Nanomaterial-Enabled Rapid Electrochemical Biosensors for Bacterial Pathogens. In: Vyas R. (eds) Advances in Bioengineering, (2020) Springer, Singapore. https://doi.org/10.1007/978-981-15-2063-1_11