Nayana Patil

Assistant Professor

Her research interests are in epigenetics, nanoparticle synthesis and its application, nanotoxicity, nanoepigenetic toxicity and proteomics. She instigated her research from BARC, Mumbai and pursued her Ph.D in Biotechnology were she elucidated the role of epigenetics in polyextremophilic bacteria Deinococcusradiodurans with respect to DNA repair and radiation resistance. Her post doctorate research her work involved identification of protein biomarkers and correlation to epigenetics in mouse and mammalian cell lines as model system.

Qualifications

Dr. D S Kothari Postdoctrate Fellow, Savitribai Phule Pune University, Pune| 2012-2014
Ph.D, BARC_UoP, Pune| 2005-2011
M.Sc, SavitribaiPhule Pune University, Pune| 2003-2005
B.ScSavitribaiPhule Pune University, Pune| 2000-2003

Experience

Teaching	7 years
Research	10 years
Industry	Nil

Career Highlights

Patent

Device for biodegradation of Sanitary napkins. Ref No. P/127/19; 201921037178

Book Chapter

Enzyme technology prospectus & their Biomedical Applications. Advances in Bioengineering, Springer Proceedings, 2020.
Epigenetic toxicity of nanoparticles. Advances in Bioengineering, Springer Proceedings, 2020

Publications

Deepti D Deobagkar, ChitraPanikar, Shriram N Rajpathak, Nayana S Shaiwale, Sanjay Mukherjee. (2012) An immunochemical method for detection and analysis of changes in methylome. Methods, Elsevier.
Nayana S. Shaiwale, D. D. Deobagkar, D. N. Deobagkar, S. K. Apte. (2015) DNA adenine hypo methylation leads to metabolic rewiring in Deinococcusradiodurans. Journal of Proteomics, Elsevier.
NayanaShaiwale, R. R. Kulkarni, D N Deobagkar, DD Deobagkar. (2015) Synthesis and extracellular accumulation of silver nanoparticles by employing radiation-resistant Deinococcusradiodurans, their characterization, and determination of bioactivity. International Journal of Nanomedicine.
Nayana Patil, W. N. Gade, D. D. Deobagkar. (2016) Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation. International Journal of Nanomedicine.
Nayana Patil, B. Basu, D.D Deobagkar; S.K. Apte, D.N. Deobagkar. (2017) Putative DNA modification methylase DR_C0020 of Deinococcusradiodurans is an atypical SAM dependent C-5 cytosine DNA methylase. BBA General Subjects, Elsevier.
NayanaPatil, PayalChandak. (2020) Microbial Keratinolytic Enzymes For Biodegradation Of Poultry Waste And Hide Depilation. Journal of Scientific & Industrial Research.

International Competition

Mentor for MITADTBIO_Pune team. Our team won iBec competition and received a grant of Rs. 10 lakh from DBT
We won Bronze medal while competing with 324 teams from all over the world in iGEM Giant Jamboree 2019, held at Boston USA.

Paper presented in International Conferences

1. Generation of adenine and cytosine methylase gene knockout mutants and study of its response to gamma radiation. International Conference on Advances in Free Radical Research held at CSIR-IITR, Lucknow, 2009.
Proteomic modulation in adenine and cytosine methylase gene knockout mutants. International Conference on Proteomics beyond ID’s held at National Chemical Laboratory (NCL), Pune, 2012.
Investigating the effect of nanoparticles on mortality and development in Drosophila melanogaster. International Conference on Nanomaterials and Nanotechnology held at VinobaBhave Research Institute, Allahabad, 2017.
Identification of Microbial Lipase and Optimization of its Biocatalytic Activity. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2018.
Microbial Keratinase and its Multi-Functional Biocatalytic Applications. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2018.
Production and Characterization of Hydrophobic Bacterial Cellulose for Fabrics. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2018.
Proteomics and Nanoepigenetic Toxicity Analysis of Lung Fibroblast Cells Exposed to Metal Oxide Nanoparticles. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2018.
Screening, Isolation, and Antibacterial Activity of Antibiotic Producing Bacteria Obtained from Mangrove Soil Samples. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2018.
Azo dye degradation by bacteria isolated from the mangrove area. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2019.
Screening of Chitinase producing bacteria from mangrove soil. International conference on recent trends in Bio-engineering held at MIT School of Bio-engineering Sciences and Research, Pune, 2019.
Isolation, characterization and identification of extremophiles from the marine ecosystem. International Conference on Advances in Medical and Industrial Biotechnology, Sathyabama Institute of Science and Technology, Chennai, 2019.
In silico docking analysis of cry and cyt toxins against dipteran models. International conference on recent trends in bio-engineering held at MIT School of Bio-Engineering Sciences and Research, Pune, 2019.
Screening and strain improvement of auxin producing bacteria. International conference on recent trends in bio-engineering held at MIT School of Bio-Engineering Sciences and Research, Pune, 2019.
Dye degradation and simultaneous bio electricity generation using microbial fuel cell. ICABET, held at Heritage Institute of Technology, Kolkata 2020.
Exploring mangrove soil microbes for cellulolytic activity. International conference on recent trends in bio-engineering held at MIT School of Bio-Engineering Sciences and Research, Pune, 2021.
Synthesis of silver nanoparticle by the most radiation resistant bacteria Deinococcusradiodurans and its application as green nanophotocatalysts. International conference on recent trends in bio-engineering held at MIT School of Bio-Engineering Sciences and Research, Pune, 2021.

Paper presented in National Conferences

Detection of DNA methylation in radiation resistant bacteria Deinococcusradiodurans. Life Sciences Symposium held at Bhabha Atomic Research Centre (BARC), Mumbai, 2007.
Modulation of DNA methylation and methylase activity in response to gamma radiation. DAE-BRNS meeting RADON held at Bhabha Atomic Research Centre (BARC), Mumbai, 2008.
Cloning, purification and Biochemical characterization of adenine and cytosine methylase from Deinococcusradiodurans. Association of Microbiologist of India, held at National Chemical Laboratory (NCL), Pune, 2009.
Synthesis and extracellular accumulation of silver nanoparticles by employing radiation-resistant Deinococcusradiodurans. Recent trends in Biotechnology held at Department of Zoology, University of Pune, Pune, 2011.
Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation. National seminar on Epigenetics held at Institute of Bioinformatics & Biotechnology (IBB), SPPU, Pune, 2016.
Green nanophotocatalysis application of silver nanoparticles synthesized byDeinococcusradiodurans. Faunal Diversity: Assessment and Conservation held at Modern College of Arts, Science & Commerce, Pune, 2016.
Biochemical characterization and Optimization of hydrolytic enzymes from Bacillus. Faunal Diversity: Assessment and Conservation held at Modern College of Arts, Science & Commerce, Pune, 2016.