Synthetic Biology Research


Synthetic Biology is a newly emerging multidisciplinary scientific field. Whichcan be defined as an extreme genetic engineering or next generation genetic engineering. Engineering principles are applied in Biology. Which involve re-designing/ re-engineering a living system (design artificial organism) that can synthesise a product that does not exist in nature, to full fill the specific needs of humans and for the wellbeing of the environment. To do so synthetic biology intersect with several other established scientific fields like computational modelling, genetic systems and circuit design, cell design and construction, assembly platforms, DNA synthesis, synthetic metagenomics, pathway construction, gene optimization, viral, protein and metabolic engineering, programmed evolution, cellular manufacturing, mathematical modelling and engineering processes. Today Synthetic Biology can be applied in the fields like medicine, agriculture, biofuels/ energy, chemistry and environment. Further synthetic Biology can provide new solutions even in the newly emerging fields like genome editing, personalized medicine etc.In our institute we are currently involved with design and construction of genetic circuit capable of degrading polymers present in sanitary napkins.

  • Gradient PCR machines
  • 2D Proteomics set up
  • Sterile room with a laminar flow
  • Electrophoresis chambers for DNA
  • Floor Shaker/incubator
  • Gel documentation system
  • Western Trans-blotting apparatus
  • Microplate reader
  • Table top refrigerated centrifuges
  • Refrigerated Microcentrifuges
  • Milli-Q water system
  • Autoclave
  • Ice machine
  • -20˚C and -80˚C freezers


1. Received funding of 10 lakh from DBT, government of India to participate in iGEM competition 2019 held at Boston, USA.

2. Received best poster award at iGEM all India meet held at Bhopal.

3. Received bronze medal at “iGEM competition 2019” held at Boston, USA


1. Nayana S. Shaiwale, D. D. Deobagkar, D. N. Deobagkar, S. K. Apte. (2015) DNA adenine hypomethylation leads to metabolic rewiring in Deinococcusradiodurans. Journal of Proteomics,Elsevier.
PMID: 26049032.

2. Nayana Patil, B. Basu, D.D Deobagkar; S.K. Apte, D.N. Deobagkar. (2017) Putative DNA modification methylase DR_C0020 of Deinococcusradioduransis an atypical SAM dependent C-5 cytosine DNA methylase. BBA General Subjects, Elsevier.
PMID: 28038990.

3. ChandrashekharAngadi, S. M.Manjula, A. B.Basavaradder,C. Madhura, S. S.Patil (2017) Identification of HighYielding Lines in F7GenerationRecombinant Inbred
Lines (RILs) of G. hirsutum ×G. hirsutum Cotton. Environment& Ecology.

4. Madhura C,Basamma K, P.V.Kencjanagouder (2012) Assessment of geneticvariability and interrelationship amongminicore collection ofgroundnut (Arachishypogaea L.). InternationalJournal ofPlantSciences.