Research Area: Plant Biotechnology

Research Topic: Nanotechnology based bio fertilizer and pesticide for agrochemical Industry.

Research Area: Genomic Data Analysis

Research Topic: Computational analysis of Next generation sequencing data using big data analytics approach.

Publications:

1. “Obstacle Detection and Avoidance Algorithm for Autonomous Mobile Robot using 2D LiDAR”, IEEE International Conference on Computing, Communication, Control and Automation (ICCUBEA), ISBN: 978-1-5386-4008-1, 2017.

2. “Human Skin Color Detection Algorithm Optimization with CUDA”, IEEE International Conference on Computing, Communication, Control and Automation (ICCUBEA), ISBN: 978-1-5386-4008-1, 2017.

3. Big data analytics for handling NGS data and its applications in identifying cancer mutations (Advances in Bioengineering, Springer book chapter).

4. “The Obstacle Detection and Avoidance Algorithm for Robotic System using 2DLiDAR and Embedded Linux”, International Journal of Control Theory and Applications, pp.693-699, 2017.

Presentations (Oral):

1. Obstacle Detection and Avoidance Algorithm for Autonomous Mobile Robot using 2D LiDAR (ICCUBEA -2017).

2. Human Skin Color Detection Algorithm Optimization with CUDA (ICCUBEA -2017).

Research Area: Biomaterials

Research Topic: Synthesis of metal oxide nanoparticles using bio-templates and study of their biological applications

Publications: A sensitive image-based optical detection of heavy metal ions using green synthesized silver nanoparticles has been published in the International Journal of Environmental Science and Technology (Springer)

Research Area: Next Generation Sequencing and Molecular Oncology

Research Topic: Novel biomarker and therapeutic agents’ discovery against cancer

Awards:

“1st Position award for the best innovative and novel research idea” in Poster Presentation on ‘Study of the neuroprotective potential associated with dietary supplementation of Coenzyme Q10 using Drosophila melanogaster model of Alzheimer’s disease’ in ARIC- Annual Research and Innovation Conclave, Institute of Advanced Research, Gandhinagar.

Presentations:

1. ‘Coenzyme Q10 possess neuroprotective potential in Drosophila melanogaster model of Alzheimer’s disease’ at ‘The Indian Drosophila Research Conference (InDRC)’, Indian Institute of Science Education and Research Kolkata (IISER K), Kolkata, West Bengal, India.

Research Area: Cancer Biology

Research Topic: Role of unfolded protein response in gynaecological cancers

Awards: CSIR NET JRF , ARS NET

Research Area: Agricultural biotechnology

Research Topic: Genetic diversity analysis of Xanthomonas campestris pv. viticola causing
bacterial leaf spot in grapes and its management.

Research Area: Biomedical Imaging

Research Topic: Design and development of multi-disease detection model using Diagnostic Imaging Technology

Publications:

1. Madhavi P. Bhongale, Renu Vyas, Role of BioJava in the department of Bioinformatics Tools Advances in Bioengineering, Springer Nature (2020)

2. Off-line Signature Verification Using Artificial Neural Network International Journal of Emerging Technology and Advanced Engineering, Volume 3, Issue 9, September 2013 ISSN: 2250-2459, ISO 9001:2008 © IJETAE International Journals: www.ijetae.com, Madhavi D. Malekar, Sachin Patel.

3. Off-line Signature Verification Using Artificial Neural Network& Error Detection International Journal of Computer Science and Information Technologies, Volume5, Issue 4, 2014, ISSN : 0975-9646 © IJCSIT International Journals: www.ijcsit.com, Madhavi D. Malekar, Sachin Sohara.

4. Off-line Signature Verification Using ANN in Futurizm 17 organized by PDEA’s College of Engineering, Pune.

Presentations(Oral/Poster):

1. Presented paper on Detection of infectious diseases from chest X-ray and CT Images using a new Optimized Classifier in International Conference on Recent Trends in Bioengineering (ICRTB 2018) organized by MIT School of Bioengineering Sciences & Research, Pune on 12-13 February 2022.

Research Area: Onco Immunology, Antibody Engineering, Drug Discovery.

Research Topic: Antibody discovery/engineering using in silico tools.

Publications:

1. Manoj K. Sabnani, Robin Rajan, Bradley Rowland, Vikram Mavinkurve, Laurence Wood, Alberto A. Gabizon, Ninh M. La-Beck.
Liposome promotion of tumor growth and angiogenesis is associated with modulation of antitumor immune response. Nanomedicine: Nanotechnology, Biology and Medicine, Volume 11, Issue 2, 259 – 262. DOI: http://dx.doi.org/10.1016/j.nano.2014.08.010.

2. Robin Rajan, Magdalena Karbowniczek, Haley Pugsley, Manoj K. Sabnani, Aristotelis Astrinidis, Ninh M. La-Beck.
Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry. Imagestream methods: Cytometry Part A, Volume 87, Issue 5, 451 - 458. DOI: 10.1002/cyto.a.22652

3. Devin B. Lowe, Camille K. Bivens, Alexis S. Mobley, Christian E. Herrera, Amanda L. McCormick, Timea Wichner, Manoj K. Sabnani, Laurence M. Wood & Jon A. Weidanz
TCR-like antibody drug conjugates mediate killing of tumor cells with low peptide/HLA targets, mAbs, 9:4, 603-614, DOI: 10.1080/19420862.2017.1302630

4. Anuraj N, Sabnani Manoj K, Mukesh Yadav, Jyotsana Kharate J, Deepika Sharma R and Rachna Chourasia J. (2012).
Identification and characterization of proteases and amylases producing Bacillus licheniformis strain EMBS026 by 16S rRNA Gene Sequencing. International journal of Microbiology Research ISSN: 0975-5276 & E-ISSN: 0975-9174, Volume 4, Issue 5, 2012, 227-231.

5. Robin Rajan, Manoj K. Sabnani, Laurence M. Wood, Vikram   Mavinkurve, Alberto A. Gabizon and Ninh M. La-Beck.
Pegylated liposomal alendronate: The impact of the drug cargo on carrier-induced       immune modulation. American Association of Cancer Research. DOI: 10.1158/1538-7445.AM2016-4008 Published July 2016

6. SSS Peri, Manoj K Sabnani, MU Raza, S Ghaffari, S Gimlin, DD Wawro. Detection of specific antibody-ligand interactions with a self-induced back-action actuated nanopore electrophoresis sensor Nanotechnology 31 (8), 085502

7. J Kaur, MK Sabnani, BY Stephens, D Nandadeva, JA Weidanz, PJ Fadel Peripheral Blood Mononuclear Cell‐Derived Superoxide Production, Spontaneous Baroreflex Sensitivity, and Vascular Function in Chronic Kidney Disease Patients. The FASEB Journal 34 (S1), 1-1.

8. Book Chapter: Reference Module in Biomedical Sciences. Stem cells as Drug delivery vehicle DOI:10.1016/B978-0-12-801238-3.65443-0

9. Serkan Yaman, Harish Ramachandramoorthy, Gizem Oter, Daria Zhukova, Tam Nguyen, Manoj Kumar Sabnani, Jon A Weidanz* and Kytai Truong Nguyen* Melanoma Peptide MHC Specific TCR Expressing T-Cell Membrane Camouflaged PLGA Nanoparticles for Treatment of Melanoma Skin Cancer. Frontiers in Bioengineering & Biotechnology Section. (September 2020)

10. Sai Santosh Sasank Peri, Manoj Kumar Sabnani, Muhammad Usman Raza, Elizabeth L. Urquhart, Soroush Ghaffari, Jung Soo Lee, Min Jun Kim, Jon Weidanz, George Alexandrakis. Quantification of Low Affinity Binding Interactions between Natural Killer Cell Inhibitory Receptors and Targeting Ligands with a SelfInduced Back-Action Actuated Nanopore Electrophoresis (SANE) Sensor.. IOP Nanotechnology.

11.  Zaki, Magdi E.A., Sami A. Al-Hussain, Vijay H. Masand, Manoj K. Sabnani, and Abdul Samad. 2021. "Mechanistic and Predictive QSAR Analysis of Diverse Molecules to Capture Salient and Hidden Pharmacophores for Anti-Thrombotic Activity" International Journal of Molecular Sciences 22, no. 15: 8352. https://doi.org/10.3390/ijms22158352